Identification of Primordial Germ Cells: Cytological, Histological and Immunohistochemical Aspects

Identification of Primordial Germ Cells: Cytological, Histological and Immunohistochemical Aspects

Primordial germ cells (PGCs) constitute an embryonic cell type that migrate to gonadal precursors and form the gametes. In many animals, PGCs are set apart from somatic cells early during embryogenesis. These cells migrate to gonadal precursors and then constitute gonads so they are useful models for cell motility studies. They have a highlighted importance for development and reproduction stud...

Lymphomas of the maxillofacial region – cytological, histological and immunohistochemical aspects

A. IACOB , A. ORMENIȘAN , T. MEZEI , A. ZAZGYVA *, A. SIN , M. TILINCA (3) 1 Department of Oral and Maxillofacial Surgery, University of Medicine and Pharmacy of Târgu Mureş, Târgu Mureş , Romania 2 Department of Pathology, University of Medicine and Pharmacy of Târgu Mureş, Târgu Mureş , Romania 3 Department of Cell and Molecular Biology, University of Medicine and Pharmacy of Târgu Mureş, Târ...

Pterygium: histological and immunohistochemical aspects.

INTRODUCTION Pterygium represents a triangular conjunctivo-epithelial overgrowth, proliferating from the bulbar conjunctiva and covering the cornea, causing severe vision loss. It is an abnormal growth and differentiation of the conjunctive epithelial structures of the corneal limbus. Chronic exposures to solar ultraviolet radiation, heat and dust, as well as viral agents, are the most common p...

Primordial germ cells migration: morphological and molecular aspects

Primordial germ cells (PGCs) are germline stem cells that give rise to gametes in vertebrates. They originate outside the embryo very early in development and migrate by a well-defined route into the genital ridges. During early embryogenesis in mammals, the PGCs are observed in an extra-embryonic region near the yolk sac, translocate to the endodermal epithelium of the hindgut as embryogenesis...

Functional Concentrations of BMP4 on Differentiation of Mouse Embryonic Stem Cells to Primordial Germ Cells